The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in h...
The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in hepatocellular carcinoma
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Author / Creator
Kanzaki, Hiroaki , Chiba, Tetsuhiro , Ao, Junjie , Koroki, Keisuke , Kanayama, Kengo , Maruta, Susumu , Maeda, Takahiro , Kusakabe, Yuko , Kobayashi, Kazufumi , Kanogawa, Naoya , Kiyono, Soichiro , Nakamura, Masato , Kondo, Takayuki , Saito, Tomoko , Nakagawa, Ryo , Ogasawara, Sadahisa , Suzuki, Eiichiro , Ooka, Yoshihiko , Muroyama, Ryosuke , Nakamoto, Shingo , Yasui, Shin , Tawada, Akinobu , Arai, Makoto , Kanda, Tatsuo , Maruyama, Hitoshi , Mimura, Naoya , Kato, Jun , Zen, Yoh , Ohtsuka, Masayuki , Iwama, Atsushi and Kato, Naoya
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
FGF19/FGFR4 autocrine signaling is one of the main targets for multi-kinase inhibitors (MKIs). However, the molecular mechanisms underlying FGF19/FGFR4 signaling in the antitumor effects to MKIs in hepatocellular carcinoma (HCC) remain unclear. In this study, the impact of FGFR4/ERK signaling inhibition on HCC following MKI treatment was analyzed i...
Alternative Titles
Full title
The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Chiba, Tetsuhiro
Ao, Junjie
Koroki, Keisuke
Kanayama, Kengo
Maruta, Susumu
Maeda, Takahiro
Kusakabe, Yuko
Kobayashi, Kazufumi
Kanogawa, Naoya
Kiyono, Soichiro
Nakamura, Masato
Kondo, Takayuki
Saito, Tomoko
Nakagawa, Ryo
Ogasawara, Sadahisa
Suzuki, Eiichiro
Ooka, Yoshihiko
Muroyama, Ryosuke
Nakamoto, Shingo
Yasui, Shin
Tawada, Akinobu
Arai, Makoto
Kanda, Tatsuo
Maruyama, Hitoshi
Mimura, Naoya
Kato, Jun
Zen, Yoh
Ohtsuka, Masayuki
Iwama, Atsushi
Kato, Naoya
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_291df543461344c18b5823f3f97cddec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_291df543461344c18b5823f3f97cddec
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-84117-9
