GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
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Author / Creator
Estonian Biobank , DBDS Genomic Consortium , Skuladottir, Astros Th , Stefansdottir, Lilja , Halldorsson, Gisli H. , Stefansson, Olafur A. , Bjornsdottir, Anna , Jonsson, Palmi , Palmadottir, Vala , Thorgeirsson, Thorgeir E. , Walters, G. Bragi , Gisladottir, Rosa S. , Bjornsdottir, Gyda , Jonsdottir, Gudrun A. , Sulem, Patrick , Gudbjartsson, Daniel F. , Knowlton, Kirk U. , Jones, David A. , Ottas, Aigar , Pedersen, Ole B. , Didriksen, Maria , Brunak, Søren , Banasik, Karina , Hansen, Thomas Folkmann , Erikstrup, Christian , Haavik, Jan , Andreassen, Ole A. , Rye, David , Igland, Jannicke , Ostrowski, Sisse Rye , Milani, Lili A. , Nadauld, Lincoln D. , Stefansson, Hreinn and Stefansson, Kari
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Essential tremor (ET) is a prevalent neurological disorder with a largely unknown underlying biology. In this genome-wide association study meta-analysis, comprising 16,480 ET cases and 1,936,173 controls from seven datasets, we identify 12 sequence variants at 11 loci. Evaluating mRNA expression, splicing, plasma protein levels, and coding effects...
Alternative Titles
Full title
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis
Authors, Artists and Contributors
Author / Creator
DBDS Genomic Consortium
Skuladottir, Astros Th
Stefansdottir, Lilja
Halldorsson, Gisli H.
Stefansson, Olafur A.
Bjornsdottir, Anna
Jonsson, Palmi
Palmadottir, Vala
Thorgeirsson, Thorgeir E.
Walters, G. Bragi
Gisladottir, Rosa S.
Bjornsdottir, Gyda
Jonsdottir, Gudrun A.
Sulem, Patrick
Gudbjartsson, Daniel F.
Knowlton, Kirk U.
Jones, David A.
Ottas, Aigar
Pedersen, Ole B.
Didriksen, Maria
Brunak, Søren
Banasik, Karina
Hansen, Thomas Folkmann
Erikstrup, Christian
Haavik, Jan
Andreassen, Ole A.
Rye, David
Igland, Jannicke
Ostrowski, Sisse Rye
Milani, Lili A.
Nadauld, Lincoln D.
Stefansson, Hreinn
Stefansson, Kari
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_292c62d4e1144f90932fbbfa2deb5465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_292c62d4e1144f90932fbbfa2deb5465
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-06207-4
