METTL1-mediated tRNA m7G methylation and translational dysfunction restricts breast cancer tumorigen...
METTL1-mediated tRNA m7G methylation and translational dysfunction restricts breast cancer tumorigenesis by fueling cell cycle blockade
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Author / Creator
Du, Dan , Zhou, Mingxia , Ju, Chenxi , Yin, Jie , Wang, Chang , Xu, Xinyu , Yang, Yunqing , Li, Yun , Cui, Le , Wang, Zhengyang , Lei, Yuqing , Li, Hongle , He, Fucheng and He, Jing
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background RNA modifications of transfer RNAs (tRNAs) are critical for tRNA function. Growing evidence has revealed that tRNA modifications are related to various disease processes, including malignant tumors. However, the biological functions of methyltransferase-like 1 (METTL1)-regulated m.sup.7G tRNA modifications in breast cancer (BC) remain la...
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Full title
METTL1-mediated tRNA m7G methylation and translational dysfunction restricts breast cancer tumorigenesis by fueling cell cycle blockade
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2952b19721fd42eeae5d67470604132e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2952b19721fd42eeae5d67470604132e
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-024-03076-x
