Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma
Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma
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Author / Creator
Zhao, Yan , Patel, Jenil , Fan, Jinhua , Wang, Xinyang , Chen, Lin , Li, Yuanyuan and Luo, Zhengxiu
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Airway epithelial cells constitute the first line of defense against external noxious stimuli and play crucial roles in the release of epithelial inflammatory cytokines (IL33, IL25 and TSLP), initiating airway allergic inflammatory diseases such as asthma. IL33 plays critical physiological processes in T2-endotype asthma. However, the mechanisms by...
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Full title
Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma
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TN_cdi_doaj_primary_oai_doaj_org_article_2966cd7a47ed455b898a51366545b29a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2966cd7a47ed455b898a51366545b29a
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-025-06116-y