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Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2966cd7a47ed455b898a51366545b29a

Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

About this item

Full title

Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2025-02, Vol.23 (1), p.203-13, Article 203

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Airway epithelial cells constitute the first line of defense against external noxious stimuli and play crucial roles in the release of epithelial inflammatory cytokines (IL33, IL25 and TSLP), initiating airway allergic inflammatory diseases such as asthma. IL33 plays critical physiological processes in T2-endotype asthma. However, the mechanisms by...

Alternative Titles

Full title

Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2966cd7a47ed455b898a51366545b29a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2966cd7a47ed455b898a51366545b29a

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-025-06116-y

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