Node-sparing modified short-course Radiotherapy Combined with CAPOX and Tislelizumab for locally Adv...
Node-sparing modified short-course Radiotherapy Combined with CAPOX and Tislelizumab for locally Advanced MSS of Middle and low rectal Cancer (mRCAT): an open-label, single-arm, prospective, multicentre clinical trial
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Author / Creator
Cai, Cheng , Zhang, Xia , Sun, Xiaonan , Wang, Huogang , Chen, Engeng , Chen, Li , Gu, Benxing , Wang, Jianping , Huang, Xuefeng , Lao, Weifeng , Wang, Xiaowei , Chen, Min , Ding, Shubo , Du, Jinlin and Song, Zhangfa
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Neoadjuvant chemoradiotherapy followed by total mesorectal excision is a standard treatment for locally advanced rectal cancer. Mismatch repair-deficient locally advanced rectal cancer (LARC) was highly sensitive to PD-1 blockade. However, most rectal cancers are microsatellite stable (MSS) or mismatch repair-proficient (pMMR) subtypes for which PD...
Alternative Titles
Full title
Node-sparing modified short-course Radiotherapy Combined with CAPOX and Tislelizumab for locally Advanced MSS of Middle and low rectal Cancer (mRCAT): an open-label, single-arm, prospective, multicentre clinical trial
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_298fbfc86d9f426ea7c57f5b038fe729
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_298fbfc86d9f426ea7c57f5b038fe729
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-024-12994-0
