Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans
Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The asparagine (N)-linked Man9GlcNAc2 is required for glycoprotein folding and secretion. Understanding how its structure contributes to these functions has been stymied by our inability to produce this glycan as a homogenous structure of sufficient quantities for study. Here, we report the high yield chemoenzymatic synthesis of Man9GlcNAc2 and its...
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Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans
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TN_cdi_doaj_primary_oai_doaj_org_article_29a5c7cd42d945a9960434571e434f91
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29a5c7cd42d945a9960434571e434f91
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09752-3