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Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans

Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29a5c7cd42d945a9960434571e434f91

Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans

About this item

Full title

Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-04, Vol.10 (1), p.1813-1813, Article 1813

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The asparagine (N)-linked Man9GlcNAc2 is required for glycoprotein folding and secretion. Understanding how its structure contributes to these functions has been stymied by our inability to produce this glycan as a homogenous structure of sufficient quantities for study. Here, we report the high yield chemoenzymatic synthesis of Man9GlcNAc2 and its...

Alternative Titles

Full title

Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_29a5c7cd42d945a9960434571e434f91

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29a5c7cd42d945a9960434571e434f91

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-09752-3

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