In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucl...
In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ribosomes comprise a large (LSU) and a small subunit (SSU) which are synthesized independently in the nucleolus before being exported into the cytoplasm, where they assemble into functional ribosomes. Individual maturation steps have been analyzed in detail using biochemical methods, light microscopy and conventional electron microscopy (EM). In re...
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In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli
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TN_cdi_doaj_primary_oai_doaj_org_article_29af8d2ce12c4b48a297291bce32bf53
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29af8d2ce12c4b48a297291bce32bf53
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25413-w