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CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent ste...

CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent ste...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29db2a3441fd43ac814796411500c5ee

CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

About this item

Full title

CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2022-01, Vol.20 (1), p.8-15, Article 8

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The application of CRISPR/Cas9 technology in human induced pluripotent stem cells (hiPSC) holds tremendous potential for basic research and cell-based gene therapy. However, the fulfillment of these promises relies on the capacity to efficiently deliver exogenous nucleic acids and harness the repair mechanisms induced by the nuclease activity in or...

Alternative Titles

Full title

CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_29db2a3441fd43ac814796411500c5ee

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29db2a3441fd43ac814796411500c5ee

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-021-01214-x

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