CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent ste...
CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles
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Author / Creator
Mianné, Joffrey , Nasri, Amel , Van, Chloé Nguyen , Bourguignon, Chloé , Fieldès, Mathieu , Ahmed, Engi , Duthoit, Christine , Martin, Nicolas , Parrinello, Hugues , Louis, Anaïs , Iché, Alexandra , Gayon, Régis , Samain, Florine , Lamouroux, Lucille , Bouillé, Pascale , Bourdin, Arnaud , Assou, Said and De Vos, John
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The application of CRISPR/Cas9 technology in human induced pluripotent stem cells (hiPSC) holds tremendous potential for basic research and cell-based gene therapy. However, the fulfillment of these promises relies on the capacity to efficiently deliver exogenous nucleic acids and harness the repair mechanisms induced by the nuclease activity in or...
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Full title
CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_29db2a3441fd43ac814796411500c5ee
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29db2a3441fd43ac814796411500c5ee
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-021-01214-x