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Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene express...

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene express...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a178227546947689b7deca1eadc1b03

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

About this item

Full title

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2020-03, Vol.15 (1), p.15-15, Article 15

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Recombinant adeno-associated virus (rAAV) is widely used in the neuroscience field to manipulate gene expression in the nervous system. However, a limitation to the use of rAAV vectors is the time and expense needed to produce them. To overcome this limitation, we evaluated whether unpurified rAAV vectors secreted into the media following scalable...

Alternative Titles

Full title

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2a178227546947689b7deca1eadc1b03

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a178227546947689b7deca1eadc1b03

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-020-00361-z

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