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The effect of protein mutations on drug binding suggests ensuing personalised drug selection

The effect of protein mutations on drug binding suggests ensuing personalised drug selection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a363102d41c4c2d90161fca91a7f1ec

The effect of protein mutations on drug binding suggests ensuing personalised drug selection

About this item

Full title

The effect of protein mutations on drug binding suggests ensuing personalised drug selection

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-06, Vol.11 (1), p.13452-13452, Article 13452

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The advent of personalised medicine promises a deeper understanding of mechanisms and therefore therapies. However, the connection between genomic sequences and clinical treatments is often unclear. We studied 50 breast cancer patients belonging to a population-cohort in the state of Qatar. From Sanger sequencing, we identified several new deleteri...

Alternative Titles

Full title

The effect of protein mutations on drug binding suggests ensuing personalised drug selection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2a363102d41c4c2d90161fca91a7f1ec

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a363102d41c4c2d90161fca91a7f1ec

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-92785-w

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