IL-1β-induced epithelial cell and fibroblast transdifferentiation promotes neutrophil recruitment in...
IL-1β-induced epithelial cell and fibroblast transdifferentiation promotes neutrophil recruitment in chronic rhinosinusitis with nasal polyps
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Author / Creator
Xie, Xinyu , Wang, Pin , Jin, Min , Wang, Yue , Qi, Lijie , Wu, Changhua , Guo, Shu , Li, Changqing , Zhang, Xiaojun , Yuan, Ye , Ma, Xinyi , Liu, Fangying , Liu, Weiyuan , Liu, Heng , Duan, Chen , Ye, Ping , Li, Xuezhong , Borish, Larry , Zhao, Wei and Feng, Xin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Neutrophilic inflammation contributes to multiple chronic inflammatory airway diseases, including asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), and is associated with an unfavorable prognosis. Here, using single-cell RNA sequencing (scRNA-seq) to profile human nasal mucosa obtained from the inferior turbinates, middle turbinates, an...
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Full title
IL-1β-induced epithelial cell and fibroblast transdifferentiation promotes neutrophil recruitment in chronic rhinosinusitis with nasal polyps
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TN_cdi_doaj_primary_oai_doaj_org_article_2a3f8f03b3ce4e50a52456454498b282
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a3f8f03b3ce4e50a52456454498b282
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53307-0
