Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix So...
Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix Softness Induced Histone H3 Modifications
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Germany: John Wiley & Sons, Inc
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English
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Publisher
Germany: John Wiley & Sons, Inc
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The physical microenvironment is a critical mediator of tumor behavior. However, detailed biological and mechanistic insight is lacking. The present study reveals the role of chemotherapy‐enriched CD133+ liver cancer stem cells (CSCs) with THBS2 deficiency. This subpopulation of cells contributes to a more aggressive cancer and functional stemness...
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Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix Softness Induced Histone H3 Modifications
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TN_cdi_doaj_primary_oai_doaj_org_article_2a5ef7c2238c47aa96ef20b3f5aacb10
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a5ef7c2238c47aa96ef20b3f5aacb10
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202002483
