Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late anti...
Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Infiltration of Ly6C(hi) monocytes from the blood is a hallmark of viral encephalitis. In mice with lethal encephalitis caused by West Nile virus (WNV), an emerging neurotropic flavivirus, inhibition of Ly6C(hi) monocyte trafficking into the brain by anti-very late antigen (VLA)-4 integrin antibody blockade at the time of first weight loss and leuk...
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Targeted blockade in lethal West Nile virus encephalitis indicates a crucial role for very late antigen (VLA)-4-dependent recruitment of nitric oxide-producing macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_2a74fce0f81c4a14900b869bcbc497b2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2a74fce0f81c4a14900b869bcbc497b2
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/1742-2094-9-246
