Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency...
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
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Author / Creator
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States) , Zhao, Fangzhu , Berndsen, Zachary T. , Pedreño-Lopez, Nuria , Burns, Alison , Allen, Joel D. , Barman, Shawn , Lee, Wen-Hsin , Chakraborty, Srirupa , Gnanakaran, Sandrasegaram , Sewall, Leigh M. , Ozorowski, Gabriel , Limbo, Oliver , Song, Ge , Yong, Peter , Callaghan, Sean , Coppola, Jessica , Weisgrau, Kim L. , Lifson, Jeffrey D. , Nedellec, Rebecca , Voigt, Thomas B. , Laurino, Fernanda , Louw, Johan , Rosen, Brandon C. , Ricciardi, Michael , Crispin, Max , Desrosiers, Ronald C. , Rakasz, Eva G. , Watkins, David I. , Andrabi, Raiees , Ward, Andrew B. , Burton, Dennis R. and Sok, Devin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
SIVmac239 infection of macaques is a favored model of human HIV infection. However, the SIVmac239 envelope (Env) trimer structure, glycan occupancy, and the targets and ability of neutralizing antibodies (nAbs) to protect against SIVmac239 remain unknown. Here, we report the isolation of SIVmac239 nAbs that recognize a glycan hole and the V1/V4 loo...
Alternative Titles
Full title
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
Authors, Artists and Contributors
Author / Creator
Zhao, Fangzhu
Berndsen, Zachary T.
Pedreño-Lopez, Nuria
Burns, Alison
Allen, Joel D.
Barman, Shawn
Lee, Wen-Hsin
Chakraborty, Srirupa
Gnanakaran, Sandrasegaram
Sewall, Leigh M.
Ozorowski, Gabriel
Limbo, Oliver
Song, Ge
Yong, Peter
Callaghan, Sean
Coppola, Jessica
Weisgrau, Kim L.
Lifson, Jeffrey D.
Nedellec, Rebecca
Voigt, Thomas B.
Laurino, Fernanda
Louw, Johan
Rosen, Brandon C.
Ricciardi, Michael
Crispin, Max
Desrosiers, Ronald C.
Rakasz, Eva G.
Watkins, David I.
Andrabi, Raiees
Ward, Andrew B.
Burton, Dennis R.
Sok, Devin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2aa7798e6f944e178232a7a70fe98e0c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2aa7798e6f944e178232a7a70fe98e0c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32783-2
