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Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attention...

Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attention...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2aca38124f6b4bf6abea581f18e3486f

Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

About this item

Full title

Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2021-01, Vol.4 (1), p.59-21, Article 59

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The NMDA receptor-mediated Ca
2+
 signaling during simultaneous pre- and postsynaptic activity is critically involved in synaptic plasticity and thus has a key role in the nervous system. In
GRIN2
-variant patients alterations of this coincidence detection provoked complex clinical phenotypes, ranging from reduced muscle strength to epi...

Alternative Titles

Full title

Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2aca38124f6b4bf6abea581f18e3486f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2aca38124f6b4bf6abea581f18e3486f

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-020-01538-4

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