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High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in...

High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ae9d397d3764417a027e9cbb10c10b1

High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

About this item

Full title

High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

Publisher

England: John Wiley & Sons, Inc

Journal title

FEBS open bio, 2017-09, Vol.7 (9), p.1410-1421

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Aldosterone synthase is the key rate‐limiting enzyme in adrenal aldosterone production, and induction of its gene (CYP11B2) results in the progression of hypertension. As hypertension is a frequent complication among patients with diabetes, we set out to elucidate the link between diabetes mellitus and hypertension. We examined the effects of high...

Alternative Titles

Full title

High glucose stimulates expression of aldosterone synthase (CYP11B2) and secretion of aldosterone in human adrenal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2ae9d397d3764417a027e9cbb10c10b1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ae9d397d3764417a027e9cbb10c10b1

Other Identifiers

ISSN

2211-5463

E-ISSN

2211-5463

DOI

10.1002/2211-5463.12277

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