MKK6 controls T3-mediated browning of white adipose tissue
MKK6 controls T3-mediated browning of white adipose tissue
About this item
Full title
Author / Creator
Matesanz, Nuria , Bernardo, Edgar , Acín-Pérez, Rebeca , Manieri, Elisa , Pérez-Sieira, Sonia , Hernández-Cosido, Lourdes , Montalvo-Romeral, Valle , Mora, Alfonso , Rodríguez, Elena , Leiva-Vega, Luis , Lechuga-Vieco, Ana Victoria , Ruiz-Cabello, Jesús , Torres, Jorge L. , Crespo-Ruiz, Maria , Centeno, Francisco , Álvarez, Clara V. , Marcos, Miguel , Enríquez, Jose Antonio , Nogueiras, Ruben and Sabio, Guadalupe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Increasing the thermogenic capacity of adipose tissue to enhance organismal energy expenditure is considered a promising therapeutic strategy to combat obesity. Here, we report that expression of the p38 MAPK activator MKK6 is elevated in white adipose tissue of obese individuals. Using knockout animals and shRNA, we show that
Mkk6
deletion i...
Alternative Titles
Full title
MKK6 controls T3-mediated browning of white adipose tissue
Authors, Artists and Contributors
Author / Creator
Bernardo, Edgar
Acín-Pérez, Rebeca
Manieri, Elisa
Pérez-Sieira, Sonia
Hernández-Cosido, Lourdes
Montalvo-Romeral, Valle
Mora, Alfonso
Rodríguez, Elena
Leiva-Vega, Luis
Lechuga-Vieco, Ana Victoria
Ruiz-Cabello, Jesús
Torres, Jorge L.
Crespo-Ruiz, Maria
Centeno, Francisco
Álvarez, Clara V.
Marcos, Miguel
Enríquez, Jose Antonio
Nogueiras, Ruben
Sabio, Guadalupe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2aee8a2191dc416bb7efc458ac892fc6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2aee8a2191dc416bb7efc458ac892fc6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00948-z
