Metabolic effects of bezafibrate in mitochondrial disease
Metabolic effects of bezafibrate in mitochondrial disease
About this item
Full title
Author / Creator
Steele, Hannah , Gomez‐Duran, Aurora , Pyle, Angela , Hopton, Sila , Newman, Jane , Stefanetti, Renae J , Charman, Sarah J , Parikh, Jehill D , He, Langping , Viscomi, Carlo , Jakovljevic, Djordje G , Hollingsworth, Kieren G , Robinson, Alan J , Taylor, Robert W , Bottolo, Leonardo , Horvath, Rita and Chinnery, Patrick F
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mitochondrial disorders affect 1/5,000 and have no cure. Inducing mitochondrial biogenesis with bezafibrate improves mitochondrial function in animal models, but there are no comparable human studies. We performed an open‐label observational experimental medicine study of six patients with mitochondrial myopathy caused by the m.3243A>G
MTTL1
...
Alternative Titles
Full title
Metabolic effects of bezafibrate in mitochondrial disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2afb00dd500c48f4976c29a1434a3730
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2afb00dd500c48f4976c29a1434a3730
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201911589
