Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target eff...
Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target effects
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England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Lysine deacetylases (KDACs or HDACs) are metal‐dependent enzymes that regulate lysine acetylation, a post‐translational modification that is present on thousands of human proteins, essential for many cellular processes, and often misregulated in diseases. The selective inhibition of KDACs would allow for understanding of the biological roles of ind...
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Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target effects
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TN_cdi_doaj_primary_oai_doaj_org_article_2b0a8d5f4aa142abbad2c69f8adc7808
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b0a8d5f4aa142abbad2c69f8adc7808
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ISSN
2211-5463
E-ISSN
2211-5463
DOI
10.1002/2211-5463.13896
