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Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interactio...

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interactio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b0cedcfa4ef42bca0b23b7b7cce2133

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection

About this item

Full title

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection

Publisher

England: BioMed Central Ltd

Journal title

Virology journal, 2010-11, Vol.7 (1), p.332-332, Article 332

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Host determinants of HIV-1 viral tropism include factors from producer cells that affect the efficiency of productive infection and factors in target cells that block infection after viral entry. TRIM5α restricts HIV-1 infection at an early post-entry step through a mechanism associated with rapid disassembly of the retroviral capsid. Topoisomerase...

Alternative Titles

Full title

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b0cedcfa4ef42bca0b23b7b7cce2133

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b0cedcfa4ef42bca0b23b7b7cce2133

Other Identifiers

ISSN

1743-422X

E-ISSN

1743-422X

DOI

10.1186/1743-422X-7-332

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