Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling
About this item
Full title
Author / Creator
Matsui, Kenji , Watanabe, Masahito , Yamamoto, Shutaro , Kawagoe, Shiho , Ikeda, Takumi , Ohashi, Hinari , Kuroda, Takafumi , Koda, Nagisa , Morimoto, Keita , Kinoshita, Yoshitaka , Inage, Yuka , Saito, Yatsumu , Fukunaga, Shohei , Fujimoto, Toshinari , Tajiri, Susumu , Matsumoto, Kei , Kobayashi, Eiji , Yokoo, Takashi and Yamanaka, Shuichiro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Fetal cell ablation models are crucial for studying congenital diseases, organ regeneration, and xenotransplantation. However, conventional knockout models offer limited control over disease severity, while conditional ablation models often require fetus-harming inducers. In the present study, we demonstrate that the inducible caspase 9 system enab...
Alternative Titles
Full title
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling
Authors, Artists and Contributors
Author / Creator
Watanabe, Masahito
Yamamoto, Shutaro
Kawagoe, Shiho
Ikeda, Takumi
Ohashi, Hinari
Kuroda, Takafumi
Koda, Nagisa
Morimoto, Keita
Kinoshita, Yoshitaka
Inage, Yuka
Saito, Yatsumu
Fukunaga, Shohei
Fujimoto, Toshinari
Tajiri, Susumu
Matsumoto, Kei
Kobayashi, Eiji
Yokoo, Takashi
Yamanaka, Shuichiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2b28bfcdfa754c74b3c2c4fff9988853
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b28bfcdfa754c74b3c2c4fff9988853
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57795-6
