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Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b2c812198ba450381fa3d549a94c212

Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

About this item

Full title

Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

Publisher

England: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2024-11, Vol.21 (1), p.89-17, Article 89

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Glioblastoma multiforme (GBM) is an aggressive tumor, difficult to treat pharmacologically because of the blood-brain barrier (BBB), which is rich in ATP-binding cassette (ABC) transporters and tight junction (TJ) proteins. The BBB is disrupted within GBM bulk, but it is competent in brain-adjacent-to-tumor areas, where eventual GBM foci can trigge...

Alternative Titles

Full title

Blood-brain barrier permeability increases with the differentiation of glioblastoma cells in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b2c812198ba450381fa3d549a94c212

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b2c812198ba450381fa3d549a94c212

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-024-00590-0

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