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Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate str...

Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate str...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b5f52a4226649f4a789c58cfb382738

Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate stratification of patients with extrahepatic cholangiocarcinoma

About this item

Full title

Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate stratification of patients with extrahepatic cholangiocarcinoma

Publisher

England: BioMed Central Ltd

Journal title

BMC gastroenterology, 2025-04, Vol.25 (1), p.235-20, Article 235

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Extrahepatic cholangiocarcinoma (eCCA) is a rare but refractory cancer with dense desmoplasia. Prognosis-associated stromal cells in eCCA remain poorly characterized. Here, we profiled the tumor cellular composition and identified prognosis-related stromal signatures by single-cell RNA sequencing (scRNA-seq) in eCCA. ECCA patients were further stra...

Alternative Titles

Full title

Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate stratification of patients with extrahepatic cholangiocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b5f52a4226649f4a789c58cfb382738

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b5f52a4226649f4a789c58cfb382738

Other Identifiers

ISSN

1471-230X

E-ISSN

1471-230X

DOI

10.1186/s12876-025-03829-8

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