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Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet...

Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b6507ecce2d48699f0a03d19bb7e3d3

Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome

About this item

Full title

Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome

Publisher

United States: John Wiley & Sons, Inc

Journal title

Epilepsia Open, 2024-02, Vol.9 (1), p.300-313

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Dravet syndrome is a severe epilepsy disorder that impairs learning and causes premature death. Clinical studies in patients with Dravet syndrome show that fenfluramine reduces convulsive seizures. Additional studies suggest that fenfluramine may have benefits beyond seizures, including promoting survival and improving control over emotions and beh...

Alternative Titles

Full title

Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b6507ecce2d48699f0a03d19bb7e3d3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b6507ecce2d48699f0a03d19bb7e3d3

Other Identifiers

ISSN

2470-9239

E-ISSN

2470-9239

DOI

10.1002/epi4.12873

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