Arginase 1 is a key driver of immune suppression in pancreatic cancer
Arginase 1 is a key driver of immune suppression in pancreatic cancer
About this item
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Author / Creator
Menjivar, Rosa E , Nwosu, Zeribe C , Du, Wenting , Donahue, Katelyn L , Hong, Hanna S , Espinoza, Carlos , Brown, Kristee , Velez-Delgado, Ashley , Yan, Wei , Lima, Fatima , Bischoff, Allison , Kadiyala, Padma , Salas-Escabillas, Daniel , Crawford, Howard C , Bednar, Filip , Carpenter, Eileen , Zhang, Yaqing , Halbrook, Christopher J , Lyssiotis, Costas A and Pasca di Magliano, Marina
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
An extensive fibroinflammatory stroma rich in macrophages is a hallmark of pancreatic cancer. In this disease, it is well appreciated that macrophages are immunosuppressive and contribute to the poor response to immunotherapy; however, the mechanisms of immune suppression are complex and not fully understood. Immunosuppressive macrophages are class...
Alternative Titles
Full title
Arginase 1 is a key driver of immune suppression in pancreatic cancer
Authors, Artists and Contributors
Author / Creator
Nwosu, Zeribe C
Du, Wenting
Donahue, Katelyn L
Hong, Hanna S
Espinoza, Carlos
Brown, Kristee
Velez-Delgado, Ashley
Yan, Wei
Lima, Fatima
Bischoff, Allison
Kadiyala, Padma
Salas-Escabillas, Daniel
Crawford, Howard C
Bednar, Filip
Carpenter, Eileen
Zhang, Yaqing
Halbrook, Christopher J
Lyssiotis, Costas A
Pasca di Magliano, Marina
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2b78244f89f74a1a8452e4521a5af646
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b78244f89f74a1a8452e4521a5af646
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.80721