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The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b791fb837ed48089c51d4e1c3b1fed6

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

About this item

Full title

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-09, Vol.12 (1), p.14972-15, Article 14972

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

During COVID-19 pandemic, mutations of SARS-CoV-2 produce new strains that can be more infectious or evade vaccines. Viral RNA mutations can arise from misincorporation by RNA-polymerases and modification by host factors. Analysis of SARS-CoV-2 sequence from patients showed a strong bias toward C-to-U mutation, suggesting a potential mutational rol...

Alternative Titles

Full title

The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2b791fb837ed48089c51d4e1c3b1fed6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b791fb837ed48089c51d4e1c3b1fed6

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-19067-x

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