Reference-guided de novo assembly approach improves genome reconstruction for related species
Reference-guided de novo assembly approach improves genome reconstruction for related species
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The development of next-generation sequencing has made it possible to sequence whole genomes at a relatively low cost. However, de novo genome assemblies remain challenging due to short read length, missing data, repetitive regions, polymorphisms and sequencing errors. As more and more genomes are sequenced, reference-guided assembly approaches can...
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Full title
Reference-guided de novo assembly approach improves genome reconstruction for related species
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TN_cdi_doaj_primary_oai_doaj_org_article_2b9f8b29be5e43f8ae1cdaf6b06b421b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2b9f8b29be5e43f8ae1cdaf6b06b421b
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/s12859-017-1911-6
