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Mapping mutational effects along the evolutionary landscape of HIV envelope

Mapping mutational effects along the evolutionary landscape of HIV envelope

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c00bb7d06de4f0f97a123e6ce718f88

Mapping mutational effects along the evolutionary landscape of HIV envelope

About this item

Full title

Mapping mutational effects along the evolutionary landscape of HIV envelope

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2018-03, Vol.7

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

The immediate evolutionary space accessible to HIV is largely determined by how single amino acid mutations affect fitness. These mutational effects can shift as the virus evolves. However, the prevalence of such shifts in mutational effects remains unclear. Here, we quantify the effects on viral growth of all amino acid mutations to two HIV envelo...

Alternative Titles

Full title

Mapping mutational effects along the evolutionary landscape of HIV envelope

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2c00bb7d06de4f0f97a123e6ce718f88

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c00bb7d06de4f0f97a123e6ce718f88

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.34420

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