Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
About this item
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Author / Creator
Baardman, Jeroen , Verberk, Sanne G. S. , van der Velden, Saskia , Gijbels, Marion J. J. , van Roomen, Cindy P. P. A. , Sluimer, Judith C. , Broos, Jelle Y. , Griffith, Guillermo R. , Prange, Koen H. M. , van Weeghel, Michel , Lakbir, Soufyan , Molenaar, Douwe , Meinster, Elisa , Neele, Annette E. , Kooij, Gijs , de Vries, Helga E. , Lutgens, Esther , Wellen, Kathryn E. , de Winther, Menno P. J. and Van den Bossche, Jan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, we show ATP citrate lyase (Acly) to be activated i...
Alternative Titles
Full title
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Authors, Artists and Contributors
Author / Creator
Verberk, Sanne G. S.
van der Velden, Saskia
Gijbels, Marion J. J.
van Roomen, Cindy P. P. A.
Sluimer, Judith C.
Broos, Jelle Y.
Griffith, Guillermo R.
Prange, Koen H. M.
van Weeghel, Michel
Lakbir, Soufyan
Molenaar, Douwe
Meinster, Elisa
Neele, Annette E.
Kooij, Gijs
de Vries, Helga E.
Lutgens, Esther
Wellen, Kathryn E.
de Winther, Menno P. J.
Van den Bossche, Jan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2c0a011d044046398f11e576a0b58fa9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c0a011d044046398f11e576a0b58fa9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20141-z
