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Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c373f254eb346318d878694e2b1a44e

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

About this item

Full title

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-06, Vol.15 (1), p.5046-11, Article 5046

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial respiration. Oral nicotinamide riboside (NR) increases bioavailability of NAD+ in humans. Among 90 people with PAD, t...

Alternative Titles

Full title

Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2c373f254eb346318d878694e2b1a44e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c373f254eb346318d878694e2b1a44e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-49092-5

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