Argonaute2 and LaminB modulate gene expression by controlling chromatin topology
Argonaute2 and LaminB modulate gene expression by controlling chromatin topology
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Drosophila Argonaute2 (AGO2) has been shown to regulate expression of certain loci in an RNA interference (RNAi)-independent manner, but its genome-wide function on chromatin remains unknown. Here, we identified the nuclear scaffolding protein LaminB as a novel interactor of AGO2. When either AGO2 or LaminB are depleted in Kc cells, similar transcr...
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Argonaute2 and LaminB modulate gene expression by controlling chromatin topology
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TN_cdi_doaj_primary_oai_doaj_org_article_2c73be7e19db40ceb692e211636f13eb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c73be7e19db40ceb692e211636f13eb
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007276
