Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic ef...
Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic efficacies of arming oncolytic adenovirus
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oncolytic adenoviruses (OAds), most of which are based on species C human adenovirus serotype 5 (Ad5) (OAd5), have recently received much attention as potential anticancer agents. High seroprevalence of anti-Ad5 neutralizing antibodies is a major hurdle for Ad5-based gene therapy. However, the impacts of anti-Ad5 neutralizing antibodies on OAd5-med...
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Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic efficacies of arming oncolytic adenovirus
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TN_cdi_doaj_primary_oai_doaj_org_article_2c834ccc387c4767926be3a1271e4950
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c834ccc387c4767926be3a1271e4950
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-26030-3
