Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer r...
Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The mTOR-PI3K-Akt pathway influences cell metabolism and (malignant) cell growth. We generated sex-specific polygenic risk scores capturing natural variation in 7 out of 10 top-ranked genes in this pathway. We studied the scores directly and in interaction with energy balance-related factors (body mass index (BMI), trouser/skirt size, height, physi...
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Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study
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TN_cdi_doaj_primary_oai_doaj_org_article_2c838d2530a6442893a79d5f3516e9ca
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c838d2530a6442893a79d5f3516e9ca
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ISSN
1756-0381
E-ISSN
1756-0381
DOI
10.1186/s13040-021-00286-3
