GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy p...
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
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Author / Creator
European Scleroderma Group , Australian Scleroderma Interest Group (ASIG) , López-Isac, Elena , Acosta-Herrera, Marialbert , Kerick, Martin , Assassi, Shervin , Satpathy, Ansuman T. , Granja, Jeffrey , Mumbach, Maxwell R. , Beretta, Lorenzo , Simeón, Carmen P. , Carreira, Patricia , Ortego-Centeno, Norberto , Castellvi, Ivan , Bossini-Castillo, Lara , Carmona, F. David , Orozco, Gisela , Hunzelmann, Nicolas , Distler, Jörg H. W. , Franke, Andre , Lunardi, Claudio , Moroncini, Gianluca , Gabrielli, Armando , de Vries-Bouwstra, Jeska , Wijmenga, Cisca , Koeleman, Bobby P. C. , Nordin, Annika , Padyukov, Leonid , Hoffmann-Vold, Anna-Maria , Lie, Benedicte , Proudman, Susanna , Stevens, Wendy , Nikpour, Mandana , Vyse, Timothy , Herrick, Ariane L. , Worthington, Jane , Denton, Christopher P. , Allanore, Yannick , Brown, Matthew A. , Radstake, Timothy R. D. J. , Fonseca, Carmen , Chang, Howard Y. , Mayes, Maureen D. and Martin, Javier
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Systemic sclerosis (SSc) is an autoimmune disease that shows one of the highest mortality rates among rheumatic diseases. We perform a large genome-wide association study (GWAS), and meta-analysis with previous GWASs, in 26,679 individuals and identify 27 independent genome-wide associated signals, including 13 new risk loci. The novel associations...
Alternative Titles
Full title
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
Authors, Artists and Contributors
Author / Creator
Australian Scleroderma Interest Group (ASIG)
López-Isac, Elena
Acosta-Herrera, Marialbert
Kerick, Martin
Assassi, Shervin
Satpathy, Ansuman T.
Granja, Jeffrey
Mumbach, Maxwell R.
Beretta, Lorenzo
Simeón, Carmen P.
Carreira, Patricia
Ortego-Centeno, Norberto
Castellvi, Ivan
Bossini-Castillo, Lara
Carmona, F. David
Orozco, Gisela
Hunzelmann, Nicolas
Distler, Jörg H. W.
Franke, Andre
Lunardi, Claudio
Moroncini, Gianluca
Gabrielli, Armando
de Vries-Bouwstra, Jeska
Wijmenga, Cisca
Koeleman, Bobby P. C.
Nordin, Annika
Padyukov, Leonid
Hoffmann-Vold, Anna-Maria
Lie, Benedicte
Proudman, Susanna
Stevens, Wendy
Nikpour, Mandana
Vyse, Timothy
Herrick, Ariane L.
Worthington, Jane
Denton, Christopher P.
Allanore, Yannick
Brown, Matthew A.
Radstake, Timothy R. D. J.
Fonseca, Carmen
Chang, Howard Y.
Mayes, Maureen D.
Martin, Javier
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2c83b5b19dd94142a96da7824aa29e78
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2c83b5b19dd94142a96da7824aa29e78
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12760-y
