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Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human di...

Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human di...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ca035ae75e046eb885832bba66fe865

Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models

About this item

Full title

Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-11, Vol.13 (1), p.7335-7335, Article 7335

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with systemic pathologies, including reproductive disorders in male diabetic patients. However, the molecular mechanisms that contributing to spermatogenesis dysfunction in diabetic patients have not yet been fully elucidated. Here, we perform STRT-seq to examine th...

Alternative Titles

Full title

Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2ca035ae75e046eb885832bba66fe865

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ca035ae75e046eb885832bba66fe865

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-34990-3

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