CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functional...
CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tumor-derived extracellular vesicles (EVs) are active contributors in metastasis and immunosuppression in tumor microenvironment. At least some of the EVs carry tumor surface molecules such as tumor-associated antigens (TAAs) and/or checkpoint inhibitors, and potentially could interact with T cells or CAR T cells. Upon contact with T cells, EVs cou...
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Full title
CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality
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TN_cdi_doaj_primary_oai_doaj_org_article_2cb173f3f63b4d86a4068a2d2e7d646a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2cb173f3f63b4d86a4068a2d2e7d646a
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-27604-5
