Metabolic reprogramming related to whole-chromosome instability in models for Hürthle cell carcinoma
Metabolic reprogramming related to whole-chromosome instability in models for Hürthle cell carcinoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hürthle cell carcinoma (HCC) is a recurrent subtype of non-medullary thyroid cancer. HCC is characterized by profound whole-chromosome instability (w-CIN), resulting in a near-homozygous genome (NHG), a phenomenon recently attributed to reactive oxygen species (ROS) generated during mitosis by malfunctioning mitochondria. We studied shared metaboli...
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Metabolic reprogramming related to whole-chromosome instability in models for Hürthle cell carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_2ce5b5ec0ddc4e219631f5e1d5864d47
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ce5b5ec0ddc4e219631f5e1d5864d47
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-66599-1
