Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immun...
Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization
About this item
Full title
Author / Creator
Lapuente, Dennis , Fuchs, Jana , Willar, Jonas , Vieira Antão, Ana , Eberlein, Valentina , Uhlig, Nadja , Issmail, Leila , Schmidt, Anna , Oltmanns, Friederike , Peter, Antonia Sophia , Mueller-Schmucker, Sandra , Irrgang, Pascal , Fraedrich, Kirsten , Cara, Andrea , Hoffmann, Markus , Pöhlmann, Stefan , Ensser, Armin , Pertl, Cordula , Willert, Torsten , Thirion, Christian , Grunwald, Thomas , Überla, Klaus and Tenbusch, Matthias
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Several effective SARS-CoV-2 vaccines are currently in use, but effective boosters are needed to maintain or increase immunity due to waning responses and the emergence of novel variants. Here we report that intranasal vaccinations with adenovirus 5 and 19a vectored vaccines following a systemic plasmid DNA or mRNA priming result in systemic and mu...
Alternative Titles
Full title
Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization
Authors, Artists and Contributors
Author / Creator
Fuchs, Jana
Willar, Jonas
Vieira Antão, Ana
Eberlein, Valentina
Uhlig, Nadja
Issmail, Leila
Schmidt, Anna
Oltmanns, Friederike
Peter, Antonia Sophia
Mueller-Schmucker, Sandra
Irrgang, Pascal
Fraedrich, Kirsten
Cara, Andrea
Hoffmann, Markus
Pöhlmann, Stefan
Ensser, Armin
Pertl, Cordula
Willert, Torsten
Thirion, Christian
Grunwald, Thomas
Überla, Klaus
Tenbusch, Matthias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2d658f5bfe1141c4acf2fa4bf72300b6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2d658f5bfe1141c4acf2fa4bf72300b6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27063-4
