Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degr...
Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Most eukaryotic genes express alternative polyadenylation (APA) isoforms with different 3′UTR lengths, production of which is influenced by cellular conditions. Here, we show that arsenic stress elicits global shortening of 3′UTRs through preferential usage of proximal polyadenylation sites during stress and enhanced degradation of long 3′UTR isofo...
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Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation
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TN_cdi_doaj_primary_oai_doaj_org_article_2d8fedf2c109461cb0a2b230cda92eaa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2d8fedf2c109461cb0a2b230cda92eaa
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04730-7
