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Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2dfb2ec4555549a59862ee240fc1fb9e

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

About this item

Full title

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-12, Vol.12 (1), p.21429-21429, Article 21429

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how anti-mycobacterial drugs facilitate the emergence of bacterial populations that survive throughout treatment. Using static kill curve experiments, observing two evolution cycles, it was demonst...

Alternative Titles

Full title

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2dfb2ec4555549a59862ee240fc1fb9e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2dfb2ec4555549a59862ee240fc1fb9e

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-25827-6

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