Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-...
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes
About this item
Full title
Author / Creator
Lana-Elola, Eva , Cater, Heather , Watson-Scales, Sheona , Greenaway, Simon , Müller-Winkler, Jennifer , Gibbins, Dorota , Nemes, Mihaela , Slender, Amy , Hough, Tertius , Keskivali-Bond, Piia , Scudamore, Cheryl L. , Herbert, Eleanor , Banks, Gareth T. , Mobbs, Helene , Canonica, Tara , Tosh, Justin , Noy, Suzanna , Llorian, Miriam , Nolan, Patrick M. , Griffin, Julian L. , Good, Mark , Simon, Michelle , Mallon, Ann-Marie , Wells, Sara , Fisher, Elizabeth M. C. and Tybulewicz, Victor L. J.
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: The Company of Biologists Ltd
Subjects
More information
Scope and Contents
Contents
Down syndrome (DS), trisomy 21, results in many complex phenotypes including cognitive deficits, heart defects and craniofacial alterations. Phenotypes arise from an extra copy of human chromosome 21 (Hsa21) genes. However, these dosage-sensitive causative genes remain unknown. Animal models enable identification of genes and pathological mechanism...
Alternative Titles
Full title
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes
Authors, Artists and Contributors
Author / Creator
Cater, Heather
Watson-Scales, Sheona
Greenaway, Simon
Müller-Winkler, Jennifer
Gibbins, Dorota
Nemes, Mihaela
Slender, Amy
Hough, Tertius
Keskivali-Bond, Piia
Scudamore, Cheryl L.
Herbert, Eleanor
Banks, Gareth T.
Mobbs, Helene
Canonica, Tara
Tosh, Justin
Noy, Suzanna
Llorian, Miriam
Nolan, Patrick M.
Griffin, Julian L.
Good, Mark
Simon, Michelle
Mallon, Ann-Marie
Wells, Sara
Fisher, Elizabeth M. C.
Tybulewicz, Victor L. J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2e0de4e621364f88bbb0ae2f68e17fe9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e0de4e621364f88bbb0ae2f68e17fe9
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049157
