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Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and...

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e16f962425e42da9c3a326900bb4ea8

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis

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Publication information

Publisher

England: eLife Sciences Publications Ltd

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Scope and Contents

Contents

Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal (MG) formation in cancer cells. MG mediates the glycation of proteins to form advanced glycation end products (AGEs). We have recently demonstrated that MG-induced AGEs are a common feature of breast cancer. Little is known regarding the impact of MG-mediated carbon...

Alternative Titles

Full title

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis

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Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2e16f962425e42da9c3a326900bb4ea8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e16f962425e42da9c3a326900bb4ea8

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.19375

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