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Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activa...

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e49fbf089ae4c1fa1214a974ef528d1

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

About this item

Full title

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-12, Vol.12 (1), p.22390-22390, Article 22390

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective therapeutic strategy. Our continued research protocol has exploited new optimized Passerini α-acylo...

Alternative Titles

Full title

Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2e49fbf089ae4c1fa1214a974ef528d1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e49fbf089ae4c1fa1214a974ef528d1

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-26469-4

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