Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activa...
Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective therapeutic strategy. Our continued research protocol has exploited new optimized Passerini α-acylo...
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Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators
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TN_cdi_doaj_primary_oai_doaj_org_article_2e49fbf089ae4c1fa1214a974ef528d1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e49fbf089ae4c1fa1214a974ef528d1
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-26469-4