Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-3...
Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization
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Author / Creator
Jiang, Mei , Liu, Xinghui , Zhang, Denghai , Wang, Ying , Hu, Xiaoxia , Xu, Fengxia , Jin, Mingming , Cao, Fanfan and Xu, Limin
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Acute ischemic stroke (AIS) is the most common type of cerebrovascular disease and is a leading cause of disability and death worldwide. Recently, a study suggested that transformation of microglia from the pro-inflammatory M1 state to the anti-inflammatory and tissue-reparative M2 phenotype may be an effective therapeutic strategy for ischemic str...
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Full title
Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization
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TN_cdi_doaj_primary_oai_doaj_org_article_2e51771e7c9649758f7812d08ac6469d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e51771e7c9649758f7812d08ac6469d
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-018-1124-6