Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke...
Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising tool for drug testing and modelling genetic disorders. Abnormally low upstroke velocity is a current limitation. Here we investigated the use of 3D engineered heart tissue (EHT) as a culture method with greater resemblance to human heart tissue in comparison to st...
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Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density
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TN_cdi_doaj_primary_oai_doaj_org_article_2e69ee578b0a4779a389e8f3a0ff7687
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e69ee578b0a4779a389e8f3a0ff7687
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05600-w
