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miR‐10b, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

miR‐10b, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e7230b941554f89a3d9b5e82c0d7d7f

miR‐10b, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

About this item

Full title

miR‐10b, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2012-11, Vol.4 (11), p.1214-1229

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Deregulated proliferation is a hallmark of cancer cells. Here, we show that microRNA‐10b* is a master regulator of breast cancer cell proliferation and is downregulated in tumoural samples
versus
matched peritumoural counterparts. Two canonical CpG islands (5 kb) upstream from the precursor sequence are hypermethylated in the analysed breast...

Alternative Titles

Full title

miR‐10b, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2e7230b941554f89a3d9b5e82c0d7d7f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e7230b941554f89a3d9b5e82c0d7d7f

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.1002/emmm.201201483

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