Loss of Carbamoyl Phosphate Synthetase 1 Potentiates Hepatocellular Carcinoma Metastasis by Reducing...
Loss of Carbamoyl Phosphate Synthetase 1 Potentiates Hepatocellular Carcinoma Metastasis by Reducing Aspartate Level
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Chen, Siyuan , Tang, Qin , Hu, Manqiu , Song, Sijie , Wu, Xiaohong , Zhou, You , Yang, Zihan , Liao, Siqi , Zhou, Li , Wang, Qingliang , Liu, Hongtao , Yang, Mengsu , Chen, Zhe‐Sheng , Zhao, Wei , He, Song and Zhou, Zhihang
Publisher
Germany: John Wiley & Sons, Inc
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English
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Publisher
Germany: John Wiley & Sons, Inc
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Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide. Numerous studies have shown that metabolic reprogramming is crucial for the development of HCC. Carbamoyl phosphate synthase 1 (CPS1), a rate‐limiting enzyme in urea cycle, is an abundant protein in normal hepatocytes, however, lacking systemic research in HCC. It is found...
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Loss of Carbamoyl Phosphate Synthetase 1 Potentiates Hepatocellular Carcinoma Metastasis by Reducing Aspartate Level
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TN_cdi_doaj_primary_oai_doaj_org_article_2e8952e540a94e2fa9db65bef10c5b9d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e8952e540a94e2fa9db65bef10c5b9d
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202402703