Exploiting gene dependency to inform drug development for multiple myeloma
Exploiting gene dependency to inform drug development for multiple myeloma
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Despite recent advances in therapy, multiple myeloma essentially remains an incurable malignancy. Targeting tumour-specific essential genes, which constitute a druggable dependency, potentially offers a strategy for developing new therapeutic agents to treat MM and overcome drug resistance. To explore this possibility, we analysed DepMap project da...
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Full title
Exploiting gene dependency to inform drug development for multiple myeloma
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TN_cdi_doaj_primary_oai_doaj_org_article_2e8f408a61ee410c8e747ba83971f08a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e8f408a61ee410c8e747ba83971f08a
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-16940-7
