Acute inhibition of neurosteroid estrogen synthesis suppresses status epilepticus in an animal model
Acute inhibition of neurosteroid estrogen synthesis suppresses status epilepticus in an animal model
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Status epilepticus (SE) is a common neurological emergency for which new treatments are needed. In vitro studies suggest a novel approach to controlling seizures in SE: acute inhibition of estrogen synthesis in the brain. Here, we show in rats that systemic administration of an aromatase (estrogen synthase) inhibitor after seizure onset strongly su...
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Acute inhibition of neurosteroid estrogen synthesis suppresses status epilepticus in an animal model
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TN_cdi_doaj_primary_oai_doaj_org_article_2e9ff092f3a74322b95c9d9acca8ee7d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2e9ff092f3a74322b95c9d9acca8ee7d
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.12917
