Molecular basis of V-ATPase inhibition by bafilomycin A1
Molecular basis of V-ATPase inhibition by bafilomycin A1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pharmacological inhibition of vacuolar-type H
+
-ATPase (V-ATPase) by its specific inhibitor can abrogate tumor metastasis, prevent autophagy, and reduce cellular signaling responses. Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves as a specific and potent V-ATPases inhibitor. Although there are many V-ATP...
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Molecular basis of V-ATPase inhibition by bafilomycin A1
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TN_cdi_doaj_primary_oai_doaj_org_article_2eaf386808f9439ab039a8de36118ff2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2eaf386808f9439ab039a8de36118ff2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22111-5