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Molecular basis of V-ATPase inhibition by bafilomycin A1

Molecular basis of V-ATPase inhibition by bafilomycin A1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2eaf386808f9439ab039a8de36118ff2

Molecular basis of V-ATPase inhibition by bafilomycin A1

About this item

Full title

Molecular basis of V-ATPase inhibition by bafilomycin A1

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1782-8, Article 1782

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pharmacological inhibition of vacuolar-type H
+
-ATPase (V-ATPase) by its specific inhibitor can abrogate tumor metastasis, prevent autophagy, and reduce cellular signaling responses. Bafilomycin A1, a member of macrolide antibiotics and an autophagy inhibitor, serves as a specific and potent V-ATPases inhibitor. Although there are many V-ATP...

Alternative Titles

Full title

Molecular basis of V-ATPase inhibition by bafilomycin A1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2eaf386808f9439ab039a8de36118ff2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2eaf386808f9439ab039a8de36118ff2

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22111-5

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